Endometrial/Ovarian PRP

The only ingredient necessary for the production of PRP is some peripheral blood, collected by simple blood sampling. The collected sample is placed in specially designed vials and is subsequently subjected to a high-speed centrifugation protocol in a specialized centrifuge. This process separates blood into its different components based on their density. The red blood cells stick to the bottom of the test tube and the platelets and plasma form a yellowish layer on top. The plasma is then collected and undergoes quality control, to ensure that the platelets and growth factors are in high enough concentrations to exert a therapeutic effect. Once this condition has been cleared, the resulting PRP solution is applied accordingly.

For endometrial PRP, 0.5-1 mL of PRP is infused into the endometrial cavity via an embryo transfer catheter. This process is quick, painless, requires no anaesthesia and can be performed within the clinic.

For ovarian PRP, a solution is infused into the ovary, either via the transvaginal or the laparoscopic route. The transvaginal route is similar to the egg retrieval process but instead of follicular fluid aspiration, the needle infuses the PRP solution into the ovarian stroma. Alternatively, this procedure is performed laparoscopically, meaning that the ovary is approached trans-abdominally. Laparoscopy is a minimally invasive procedure, with negligible scarring that also confers the benefit of diagnostic assessment of the female reproductive system and peritoneal cavity with unmatched accuracy (gold standard technique) and may be recommended during initial female fertility assessment. Additionally, laparoscopy facilitates the “see and treat” approach, meaning diagnosis and treatment in the same procedure for several fertility-impairing conditions, most notably endometriosis and adhesions.